Nabriva Therapeutics - PharmaKB

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Company ReportsNabriva Therapeutics

Nabriva Therapeutics(NBRV)

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Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Xenleta	Lefamulin	2020-07-27	2028-2031	Community-acquired infections , Bacterial pneumonia

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

,

cystic fibrosis

,

,

bacterial infections

,

mycoplasma infections

,

pleuropneumonia

,

mycoplasma genitalium

,

,

community-acquired pneumonia

migraine disorders

,

precursor cell lymphoblastic leukemia-lymphoma

,

hepatic insufficiency

,

,

,

transplantation

,

dermatomyositis

,

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

liver neoplasms

,

nervous system neoplasms

,

dna repair-deficiency disorders

,

hereditary congenital and neonatal diseases and abnormalities

,

,

hypoplastic anemia congenital

,

hemic and lymphatic diseases

,

adenosquamous carcinoma

,

thoracic neoplasms

,

esophageal neoplasms

,

,

squamous cell carcinoma of head and neck

,

,

,

kidney neoplasms

,

bites and stings

,

pancreatic neoplasms

,

ovarian neoplasms

,

castration-resistant prostatic neoplasms

,

myeloid leukemia acute

,

renal cell carcinoma

,

graft vs host disease

,

carcinoid tumor

,

type 1 diabetes mellitus

,

invasive hydatidiform mole

,

myeloid leukemia

,

,

,

acquired immunodeficiency syndrome

,

,

,

b-cell lymphoma

,

smoldering multiple myeloma

,

gastrointestinal neoplasms

,

urinary bladder neoplasms

,

,

,

uterine neoplasms

,

female genital neoplasms

,

hematopoietic stem cell transplantation

,

thyroid neoplasms

,

endocrine gland neoplasms

,

parathyroid neoplasms

,

,

giant cell tumors

,

,

second primary neoplasms

,

chronic urticaria

,

parkinson disease

,

aplastic anemia

,

mucocutaneous lymph node syndrome

,

fallopian tube neoplasms

,

,

urologic neoplasms

,

transitional cell carcinoma

,

ureteral neoplasms

,

serotonin syndrome

,

malignant pleural effusion

,

circulating neoplastic cells

,

myelomonocytic leukemia juvenile

,

bcr-abl positive chronic myelogenous leukemia

,

,

replacement arthroplasty hip

,

,

aneurysmal bone cysts

,

giant cell granuloma

,

,

chondroblastoma

,

deglutition disorders

,

,

brain neoplasms

,

kidney transplantation

,

graft rejection

,

psychology rejection

,

triple negative breast neoplasms

,

,

,

breast neoplasms

,

non-small-cell lung carcinoma

,

neoplasm metastasis

,

multiple myeloma

,

rectal neoplasms

,

,

colonic neoplasms

,

head and neck neoplasms

,

plasma cell neoplasms

,

,

non-hodgkin lymphoma

,

prostatic neoplasms

,

hematologic neoplasms

,

myelodysplastic syndromes

,

,

,

stomach neoplasms

,

,

,

,

,

squamous cell neoplasms

,

,

,

,

,

squamous cell carcinoma

,

,

hodgkin disease

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

juvenile arthritis

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

thrombocytopenic purpura

,

,

mucinous adenocarcinoma

,

,

,

small cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

hematologic diseases

,

,

spinal cord compression

,

,

hypercholesterolemia

,

inflammatory breast neoplasms

,

,

metabolic diseases

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

ankylosing spondylitis

,

spondylarthropathies

,

spondylarthritis

,

,

febrile neutropenia

,

cardiovascular diseases

,

ventricular dysfunction

,

sezary syndrome

,

precancerous conditions

,

lymphoproliferative disorders

,

prolymphocytic leukemia

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

immunoglobulin light-chain amyloidosis

,

large granular lymphocytic leukemia

,

large-cell lymphoma immunoblastic

,

monoclonal gammopathy of undetermined significance

,

osteogenesis imperfecta

,

musculoskeletal diseases

,

blood protein disorders

,

bone marrow diseases

,

paraproteinemias

,

neoplastic processes

,

multiple endocrine neoplasia type 1

,

,

personal satisfaction

,

,

hyperlipoproteinemia type ii

,

ductal carcinoma breast

,

hemostatic disorders

,

critical illness

,

,

,

laryngeal diseases

,

,

esophageal squamous cell carcinoma

,

phenylketonurias

,

feeding and eating disorders

,

anorexia nervosa

,

,

,

,

colorectal neoplasms

,

,

,

chronic renal insufficiency

,

rheumatoid arthritis

,

kidney diseases

,

metabolic bone diseases

,

postmenopausal osteoporosis

,

,

,

healthy volunteers/patients

,

psoriatic arthritis

,

chronic kidney failure

,

renal insufficiency

,

giant cell tumor of bone

,

,

,

,

,

erythrocyte transfusion

,

primary hyperparathyroidism

,

,

,

,

autoimmune diseases

,

,

aids-related complex

,

cardiomyopathies

,

,

hyperlipidemias

,

diabetes mellitus

,

insulin resistance

,

metabolic syndrome

,

microvascular angina

,

atherosclerosis

,

hidradenitis suppurativa

,

mycobacterium avium complex

,

,

mycobacterium avium-intracellulare infection

,

mycobacterium infections

,

,

paratuberculosis

,

,

phenylketonurias

Fluoroquinolone

,

type 2 diabetes mellitus

,

long qt syndrome

,

,

alzheimer disease

,

,

,

,

,

,

photosensitivity disorders

,

chronic renal insufficiency

,

kidney diseases

,

migraine disorders

,

pulmonary arterial hypertension

,

,

coronary artery disease

,

cardiovascular abnormalities

,

erectile dysfunction

,

major depressive disorder

,

electrocardiography

,

,

,

,

rheumatoid arthritis

,

,

,

therapeutic equivalency

,

,

psychotic disorders

,

,

thrombocytopenic purpura idiopathic

,

,

renal cell carcinoma

,

polycythemia vera

,

duchenne muscular dystrophy

,

autoimmune diseases

,

orthostatic hypotension

,

acute coronary syndrome

,

lecithin cholesterol acyltransferase deficiency

,

,

lice infestations

,

restless legs syndrome

,

marijuana abuse

,

falciparum malaria

,

allergic rhinitis

,

,

retinal diseases

,

,

,

alcoholic liver cirrhosis

,

alcoholic hepatitis

,

hepatolenticular degeneration

,

,

acinetobacter infections

,

systemic lupus erythematosus

,

,

renal insufficiency

,

,

premature obstetric labor

,

premature birth

,

,

,

respiration disorders

,

,

,

,

,

human experimentation

,

myocardial ischemia

,

phase i metabolic detoxication

,

periapical periodontitis

,

,

phototoxic dermatitis

,

,

,

,

,

short bowel syndrome

,

non-alcoholic fatty liver disease

,

alcoholic fatty liver

,

smoking cessation

,

multiple endocrine neoplasia type 1

,

postpartum hemorrhage

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

respiratory syncytial virus infections

,

bacterial vaginosis

,

retinal vein occlusion

,

,

choroidal neovascularization

,

pathologic neovascularization

,

sickle cell anemia

,

,

,

pharmacokinetics

,

,

escherichia coli infections

,

,

infectious arthritis

,

,

,

,

otorhinolaryngologic diseases

,

parkinson disease

,

methicillin-resistant staphylococcus aureus

,

,

pharmacological phenomena

,

pulmonary sarcoidosis

,

,

refractive errors

,

,

pancreatic ductal carcinoma

,

systemic inflammatory response syndrome

,

,

,

,

amyotrophic lateral sclerosis

,

anastomotic leak

,

cutaneous leishmaniasis

,

mycobacterium avium-intracellulare infection

,

staphylococcal skin infections

,

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

neoplasm metastasis

,

,

anorexia nervosa

,

,

,

graft vs host disease

,

muscle spasticity

,

interstitial lung diseases

,

myeloid leukemia

,

lymphoid leukemia

,

hepatopulmonary syndrome

,

corneal injuries

,

,

rectal neoplasms

,

,

,

castration-resistant prostatic neoplasms

,

periapical diseases

,

colorectal neoplasms

,

nontuberculous mycobacterium infections

,

,

,

,

,

acquired immunodeficiency syndrome

,

,

,

,

,

community-acquired infections

,

extensively drug-resistant tuberculosis

,

multiple myeloma

,

respiratory tract diseases

,

latent tuberculosis

,

mycobacterium infections

,

myelodysplastic syndromes

,

,

infectious skin diseases

,

bacterial skin diseases

,

,

plasma cell neoplasms

,

,

prosthesis-related infections

,

wounds and injuries

,

large b-cell lymphoma diffuse

,

,

b-cell chronic lymphocytic leukemia

,

hodgkin disease

,

,

,

,

,

congenital abnormalities

,

,

healthcare-associated pneumonia

,

aids-related opportunistic infections

,

urologic diseases

,

bronchial diseases

,

myeloproliferative disorders

,

sezary syndrome

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

burkitt lymphoma

,

large-cell lymphoma immunoblastic

,

,

clostridium infections

,

meningeal tuberculosis

,

human influenza

,

enterobacteriaceae infections

,

neurogenic urinary bladder

,

biphenotypic leukemia acute

,

,

,

,

wound infection

,

abdominal abscess

,

pelvic infection

,

ovarian neoplasms

,

myelomonocytic leukemia chronic

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

hairy cell leukemia

,

testicular neoplasms

,

,

paranasal sinus diseases

,

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

intraocular lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

central nervous system neoplasms

,

,

,

phenylketonurias

,

mycobacterium tuberculosis

,

,

hematologic neoplasms

,

,

,

musculoskeletal pain

,

systolic heart failure

,

sick sinus syndrome

,

,

,

gram-positive bacterial infections

,

triple negative breast neoplasms

,

,

primary myelofibrosis

,

,

leukemia myeloid chronic atypical bcr-abl negative

,

gestational trophoblastic disease

,

ovarian epithelial carcinoma

,

neutrophilic leukemia chronic

,

trophoblastic neoplasms

,

nervous system diseases

,

hereditary congenital and neonatal diseases and abnormalities

,

neural tube defects

,

nervous system malformations

,

spinal dysraphism

,

ocular hypertension

,

open-angle glaucoma

,

,

,

sphenoid sinusitis

,

,

hematopoietic stem cell transplantation

,

prolymphocytic leukemia

,

large granular lymphocytic leukemia

,

,

small cell lung carcinoma

,

phacoemulsification

,

acute cholecystitis

,

,

esophageal and gastric varices

,

intestinal neoplasms

,

nervous system neoplasms

,

salivary gland diseases

,

neurologic manifestations

,

,

acquired joint deformities

,

,

hematologic diseases

,

acanthamoeba keratitis

,

agammaglobulinemia

,

hidradenitis suppurativa

,

,

lymph node tuberculosis

,

prostatic diseases

,

healthy volunteers/patients

,

,

urinary tract infections

,

communicable diseases

,

,

,

pulmonary tuberculosis

,

chronic obstructive pulmonary disease

,

bacterial infections

,

multidrug-resistant tuberculosis

,

helicobacter infections

,

community-acquired pneumonia

,

,

,

,

,

respiratory tract infections

,

chronic bronchitis

,

,

bacterial conjunctivitis

,

,

,

,

liver cirrhosis

,

,

,

bacterial pneumonia

,

,

cystic fibrosis

,

endophthalmitis

,

,

myeloid leukemia acute

,

,

,

,

diabetes mellitus

,

,

,

prostatic neoplasms

,

breast neoplasms

,

,

cataract extraction

,

,

febrile neutropenia

,

,

disease susceptibility

,

precursor cell lymphoblastic leukemia-lymphoma

,

disease progression

,

non-hodgkin lymphoma

,

pseudomonas infections

,

,

,

,

,

intraabdominal infections

,

,

respiratory aspiration

,

,

,

,

urinary bladder neoplasms

,

,

corneal diseases

,

,

,

cardiovascular diseases

,

,

,

maxillary sinusitis

,

critical illness

,

nephrolithiasis

,

,

,

insulin resistance

,

,

drug-related side effects and adverse reactions

,

prostatic hyperplasia

,

microbial drug resistance

,

surgical wound infection

,

retinal detachment

,

obstructive lung diseases

,

overactive urinary bladder

,

,

,

ventilator-associated pneumonia

,

,

inflammatory bowel diseases

,

dental pulp necrosis

,

postoperative pain

,

,

cardiac arrhythmias

,

cross infection

,

,

pelvic inflammatory disease

,

,

,

antibiotic prophylaxis

,

,

bacillary dysentery

,

,

mycoplasma pneumonia

,

pyogenic liver abscess

,

osteoarticular tuberculosis

,

,

ulcerative colitis

,

otitis media with effusion

,

pancreatic neoplasms

,

macular degeneration

,

pseudomonas aeruginosa

,

intravenous substance abuse

,

hypersensitivity

,

aspiration pneumonia

,

chronic periodontitis

,

corneal transplantation

,

bacterial eye infections

,

aggressive periodontitis

,

soft tissue infections

,

meningococcal meningitis

,

pancreatic cyst

,

gastroenteritis

,

postoperative complications

,

chlamydia infections

,

adaptive immunity

,

klebsiella infections

,

,

pneumococcal pneumonia

,

periapical abscess

,

patient preference

,

suppurative otitis media

,

,

,

,

contraception behavior

,

heart disease risk factors

,

glucose intolerance

,

,

,

intravitreal injections

,

patient compliance

,

metabolic syndrome

,

,

intravesical administration

,

non-muscle invasive bladder neoplasms

,

mycoplasma pneumoniae

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

kidney transplantation

,

polyomavirus infections

,

,

,

,

,

penetrating eye injuries

,

,

ophthalmologic surgical procedures

,

hepatorenal syndrome

,

,

hereditary angioedemas

,

ureteral calculi

,

,

herpesviridae infections

,

substance-related disorders

,

bacterial endocarditis

,

,

,

pulmonary infarction

,

haemophilus infections

,

,

urinary diversion

,

,

staphylococcal infections

,

,

ischemic stroke

,

bacterial drug resistance

,

staphylococcus aureus

,

,

,

pathologic dilatation

,

drug monitoring

,

deglutition disorders

,

clostridioides difficile

,

,

aortic dissection

,

,

mycoplasma infections

,

pleuropneumonia

,

,

inappropriate prescribing

,

chemical and drug induced liver injury

,

,

venous thrombosis

,

drug resistance

,

,

,

,

,

,

,

hyperaldosteronism

,

,

sleep initiation and maintenance disorders

,

,

,

,

general anesthesia

,

,

,

,

gram-negative bacterial infections

,

,

bacterial meningitis

,

central nervous system infections

,

neuromuscular blockade

,

,

,

cytomegalovirus retinitis

,

,

adenoviridae infections

,

port-wine stain

,

,

,

capillary hemangioma

,

bipolar disorder

,

autistic disorder

,

,

,

treatment-resistant schizophrenia

,

potassium deficiency

,

asymptomatic infections

,

,

,

extracorporeal circulation

,

,

,

precancerous conditions

,

,

,

stenotrophomonas maltophilia

,

percutaneous nephrolithotomy

,

,

dissociative disorders

,

,

reactive arthritis

,

chronic kidney failure

,

musculoskeletal diseases

,

catheter-related infections

,

portal hypertension

,

myocardial revascularization

,

emergency treatment

,

,

,

multiple drug resistance

,

physical exertion

,

laboratory infection

,

,

uterine hemorrhage

,

spontaneous abortion

,

blood transfusion

,

lymphatic diseases

,

traumatic brain injuries

,

pleural empyema

,

root resorption

,

persistent infection

,

torsades de pointes

healthy volunteers/patients

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

chronic progressive multiple sclerosis

,

,

,

equipment and supplies

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